Weight based dosing of drugs for overweight and obese patients undergoing blood and marrow transplantation

Background Although pharmacokinetic assays have been developed for a number of chemotherapeutic agents used in cancer medicine, the dosing of the majority of drugs, including most of those used in conditioning regimens for allogeneic HCT, is done according to patient weight. With obesity emerging as an increasing public health problem, more overweight and frankly obese…

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